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DeCS
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Descriptor English:
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Trypsin Inhibitor, Kazal Pancreatic
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Descriptor Spanish:
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Inhibidor de Tripsina Pancreática de Kazal
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Descriptor Portuguese:
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Inibidor da Tripsina Pancreática de Kazal
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Synonyms English:
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Inhibitor, Tumor-Associated Trypsin
Pancreatic Secretory Trypsin Inhibitor
SPINK1
Serine Peptidase Inhibitor, Kazal-Type 1
Serine Protease Inhibitor Kazal-Type 1
Trypsin Inhibitor Kazal Pancreatic
Trypsin Inhibitor, Tumor-Associated
Tumor-Associated Trypsin Inhibitor
Inhibitor, Tumor Associated Trypsin
Serine Peptidase Inhibitor, Kazal Type 1
Serine Protease Inhibitor Kazal Type 1
Trypsin Inhibitor, Tumor Associated
Tumor Associated Trypsin Inhibitor
Acidic Pancreatic Trypsin Inhibitor
Kazal Pancreatic Trypsin Inhibitor
Pancreatic Trypsin Secretory Inhibitor, Kazal
Pancreatic Secretory Trypsin Inhibitor, Kazal
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Tree Number:
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D12.644.822.750.500
D12.776.124.050.850
D12.776.645.688.500
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Definition English:
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A secreted KAZAL MOTIF-containing serine peptidase inhibitor that inhibits TRYPSIN. It is a protein composed of 56 amino acid residues and is different in amino acid composition and physiological activity from the Kunitz bovine pancreatic trypsin inhibitor (APROTININ). It protects against the trypsin-mediated premature activation of ENZYME PRECURSORS in the PANCREAS. Mutations in the SPINK1 gene are associated with CHRONIC PANCREATITIS. |
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Indexing Annotation English:
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/drug eff /ultrastruct permitted
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See Related English:
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Kazal Motifs
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History Note English:
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91(75); was see under TRYPSIN INHIBITORS 1975-90
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Allowable Qualifiers English:
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Record Number:
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27874
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Unique Identifier:
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D014359
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Occurrence in VHL:
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Similar:
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DeCS CID-10 LILACS
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